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Kurabayashi and Liang’s research featured on cover of Journal of Vacuum Science and Technology B



The authors on the paper were ME students Hongsuk Nam, Bo-Ram Oh, Mikai Chen, Sungjin Wi, and Da Li, as well as ME Professors Katsuo Kurabayashi and Xiaogan Liang.

The abstract reads: “The authors present a study on the evolution behaviors of the transfer characteristics of MoSand WSe2 field-effect transistor biosensors when they are subjected to tumor necrosis factor-alpha and streptavidin solutions with varying analyte concentrations. Both MoS2 and WSe2sensors exhibit very low detection limits (∼60 fM for tumor necrosis factor-alpha detection; ∼70 fM for streptavidin detection). However, WSe2 sensors exhibit the higher linear-regime sensitivities in comparison with MoS2 sensors. In particular, WSe2 sensors exhibit high linear-regime sensitivities up to ∼1.54%/fM for detecting streptavidin at a concentration of ∼70 fM. Such relatively higher sensitivities obtained from WSe2 sensors are attributed to their intrinsic ambipolar transfer characteristics, which make their ON-state carrier concentrations significantly lower than those of MoS2 sensors, and therefore, the target-molecule-induced doping effect results in more prominent channel conductance modulation in WSe2 transistor sensors than in MoS2 sensors.Furthermore, this work strongly implies that the target-molecule-induced surface scattering also plays an important role in determining the response behaviors of the sensors made from atomically layered materials. Especially, the competition between target-molecule-induced p-doping and surface-scattering effects is responsible for the sensor behavior variation observed in the p-type conduction branch of WSe2 sensors. This work advances the critical device physics highly relevant with the fabrication and implementation of reliable nanoelectronic biosensorsbased on emerging atomically layered semiconductors.”

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