ME alumnus Yue Shao is the recipient of the ProQuest Distinguished Dissertation Award. This award recognizes highly accomplished graduate students who have produced exceptional dissertations of outstanding scholarly quality in any field of study.
Yue’s thesis describes a new approach to use human pluripotent stem cells (hPSCs) including human embryonic stem cells (hESCs) to establish synthetic embryological platforms to model early human development. Yue’s thesis work on modeling human embryonic development using hPSCs in vitro has significantly broadened our understanding of the biology and developmental potential of hPSCs. Importantly, his thesis work has established a completely new territory for the development of synthetic human embryological platforms to complement scarce in vivo and ex vivo work that uses live human and non-human primate embryos, thereby opening previously undescribed avenues to advance human embryology, embryo toxicology, and reproductive medicine.
Yue graduated from ME with his PhD in 2017. His advisor was Professor Jianping Fu. Yue is currently a postdoctoral researcher at MIT.